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留言 пSuccessful Investment in Gold Demarcate the Value of Money Gold comes under the category of most valuable metals found on earth. With gold prices in Kolkata hiking day-by-day, it is wiser to invest your savings in this precious metal. Many people think that investing in gold or silver can be dangerous as per the market values gradually increases and decreases. But, most of them know that it's a good alternative for caring for your money as value of gold never diminishes. Enlightened about the qualities that make gold so appealing and lucrative, these are widely used in making of ornaments and jewelleries. To invest in gold bricks you need to be always updated with today gold price in Pune. This you can do by searching various web portals that are updating their prices as per the current stock market. The downfall of currency increased the value of gold and has resulted in flocking of investors from all across the world. Stepping into the investing business you need to be experienced. A novice in the business may find it challenging to track exact gold prices. When you're tracking gold prices always be aware of the daily market spot price. As gold price in Hyderabad changes rather quickly and on daily basis, thus choose wisely while investing as this may result in a high profit and loss gambling of money. Today gold price in Pune has gone up unpredictably high, thus it is advised to take precautions before finalizing your decisions. If you are novice then starting with a small investment can be beneficial for learning the market criteria. This will certainly help you in studying the appropriate time and amount of investing to be done for receiving good value of your money. Keeping an eye on external economic data such as the dollar indexes and stock indexes can also be helpful. One ought to consider certain things before investing money in thisgold trading business. Selling your valuables to small vendors can cost you a lot. Thus always wisely choose your investing firms that can generate good revenues. Do not invest all of your savings at a time, as in this gambling business you have to place your coins very wisely for avoiding big losses. Always keep looking for the gold price in Kolkata as per market rate. Through web portals you can easily find out all information required. Several free classified sites are often publishing gold price in Hyderabad. Looking at the tremendous rise in past few years, now more and more people are investing their money in gold investments. You get best information about Gold price in Hyderabad and gold price in Kolkata and today gold price in Pune on free classifieds sites easily. Visit site: http://gameone.club/ what is affiliate marketing wikipedia em portugues
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留言 пSELL YOUR UNUSED DOMAIN NAME WITH THESE 7 GREAT TIPS Domain Name Buying & Selling is one of the fastest moving activity that many people fail to realize. While being within that marketplace, a large number of entrepreneurs are making fair amount of profits from domain. To understand the amount of money that is at stake, you can browse through DN Journal to view the List of Top 100 Domain Name Sales. There a number of factors that determined the actual valuation of a Domain Name. Domain Names can sell for anything between from a few hundred dollars, to tens of thousands of dollars in some cases. These factors depends upon where you are in the process as well. So, it is important to understand when you can increase the value of your domain before you make the move to sell the domain name. This is the ideal situation where if you haven&rsquo;t brought a domain name yet and if you are thinking about buying and selling domain, then you are in an ideal situation. 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姓名 CraigMex
留言 пMost common Types of Cancer - Myelogenous leukemia - Acute myelogenous leukemia (AML) - Leukemia is defined as condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending to the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia. Bone marrow is soft tissue inside the hollow center of major bone. including spine, pelvis, under arm, leg. etc. Types of leukemia Leukemia can be classified into 2 types A. Acute leukemia Acute leukemia is defined as condition of rapid increase in the numbers of extreme immature white blood cells which appear in the blood stream into other parts of the body, including tissue and organs. 1. Acute lymphoblastic leukemia (ALL) Acute lymphocytic leukemia (ALL) is a type of cancer of the abnormal growth of extreme immature lymphocytes overproduced by the bone marrow and/or lymphatic system. Since it has a tendency to multiply quickly, it can lead to death to other normal white blood cells in the bone marrow and/or lympaphatic system. In ALL, lymphocytes appear immature in blood stream. Acute lymphoblastic leukemia (ALL) is most common children forms of leukemia with about 80% of all cases. 2. Acute myelogenous leukemia (AML) Acute myelogenous leukemia (AML) is a cancer of myelogenous lining cause of rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in blood stream. B. Chronic leukemia Chronic leukemia is defined as condition of slow but still excessive build up of relatively mature abnormal white blood cells. It has a tendency to spread slowly to other parts of the body through bloodstream and/or lymphatic system. 1. Chronic lymphocytic leukemia (CLL) Chronic lymphocytic leukemia (CLL) is defined as a condition of slow growth and spreading of a group of abnormal white blood cells called B-cell lymphocytes, which fight against infection in our body by produced antibodies. In CLL, B-cell lymphocytes have become abnormal and grow out of control. They appear less immature in the bloodstream. 2. Chronic myelogenous leukemia (CML) Chronic myelogenous leukemia (CML) is also defined as condition of slow growth and spreading of abnormal granulocytes. In CML, granulocytes have become abnormal and growth uncontrollably in the bone marrow and/or lymphatic system and appear less immature in the blood stream. Myelogenous leukemia A. Acute myelogenous leukemia (AML) Acute myelogenous leukemia (AML) is a cancer of myelogenous lining cause of rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in blood stream. A.1. Symptoms 1. Fatigue and pale complexion Fatigue is a result of not enough red blood cell to transport oxygen to the body cells. Pale complexion, if the disease has affected red blood cell count. 2. Infections As white blood no longer function normally in fighting against foreign invasion such as virus and bacteria. 3. Shortness of breath Due to anemia 4. Bone pain In one of more bones or in the abdomen 5. Abdominal swelling Due to spreading of the disease to the lymph nodes or infectious cause of swelling somewhere else in the body 6. Bruising easily Due to reduced blood's platelets. 7. Poor healing of minor cuts The disease has affected the function platelets. 8. Unusual bleeding As the bone marrow fails to produce enough platelets to make a normal blood clot, such as frequent nosebleeds and bleeding from the gums 9. Prolonged or severe illness It may be the cause of immune deficiency due to abnormal white blood cells. 11. Etc. A.2. Causes and risk factors 1. Age Acute myelogenous leukemia (AML) occurs mostly in adults with increased risk with age. 2. Gender Men have an increased risk of Acute myelogenous leukemia (AML) than that of women. 3. Radiation Children with previous high dose of radiotherapy and chemotherapy have an increased risk of acute lymphoblastic leukemia. 4. Exposure to environment chemicals Exposure to certain chemicals can increase risk of the disease. 5. Previous cancer treatment. Previous cancer treatment of chemotherapy and radiation therapy increase the risk of AML. 6. Smoking AML is linked to cigarette smoke, as a result of cigarette carcinogens. 7. Genetic disorders Certain inherited genetic disorders, such as Down syndrome, Fanconi anemia, IgA deficiency, etc. increase the risk of the disease. 8. Etc. A.3. Diagnosis and tests If you have some of the symptoms of the above. the first test that your doctor order is a complete blood count after a collection of your medical history and physical examination. 1. Physical examination In Physical examination, your doctor may investigate for signs of bruising, bleeding, swelling lymph nodes, etc. 2. Complete blood count Complete blood is very important if your doctor suspected there may be a sign of the development of AML. The test will reveal to your doctor the degree of abnormal white blood cell red blood cell (anemia) and platelet count (thrombocytopenia). 3. Bone marrow biopsy The test usually is done in your doctor or in hospital as a outpatient by using a thin, tube-like needle inserted into the hip to withdraw a small sample from bone marrow. The sample will be view under microscopy to look for any abnormality of granulocytes or lymphocytes. If your doctor suspect that the disease have spread to other tissue or organs, other tests may be required. 4. Other tests if necessary A.4. Prevention Increased intake of high amount of antioxidant and foods that enhance the immune system, and living a healthy life style may reduce risk of AML. c. 1. Diet a. Garlic In the study of Garlic compounds selectively kill childhood pre-B acute lymphoblastic leukemia cells in vitro without reducing T-cell function: Potential therapeutic use in the treatment of ALL. Researchers found that after oral consumption or intravenous dose of garlic extracts to volunteers, serum from these volunteers could be substituted in similar experiments to that described in this manuscript to determine optimal dosage to achieve maximal killing of ALL cells while maintaining Th1 response. b. Soy extract In a study, research found that genistein increased the potency of the chemotherapeutic agent bleomycin against the leukemia cell line HL-60, and reduced the damage this agent normally causes to normal lymphocytes, thus it may reduce normal tissue toxicity associated with chemotherapy (Lee R et al 2004). c. Tomato Tomato contain high amount of lycopene, a powerful antioxidant that have shown inhibition of leukemia of cell cycle progression and induction of differentiation in HL-60 leukemic cells. d. Carrot Carrot contains high amount of beta carotene which has shown to induce appotosis of cancer cells. In study of Cell Cycle Regulation and Induction of Apoptosis by &beta;-carotene, researchers found that in vivo study warrants further confirmation that &beta;-carotene acts as apoptosis agent in cancer cells particularly leukemia cells but not normal cells. e. Etc. 2. With nutritional supplements a. Lipoic acid and vitamin D3 Research shows that lipoic acid, used in combination with vitamin D3, support normal (versus cancerous) growth and maturation of leukemia cells (Sokoloski JA et al 1997). b. GLA and eicosapentaenoic acid (EPA) In a study, researcher found that GLA and eicosapentaenoic acid (EPA) have been shown to cause death in HL-60 leukemia cells (Gillis RC et al 2002). c. Epigallocatechin gallate In a study in 2004 by Dr. Lee, YK, found that Epigallocatechin gallate (EGCG) in green tea blocks the production of vascular endothelial growth factor (VEGF), considered essential for leukemia growth and spread. d. Lycopene and 1,25-dihydroxyvitamin D3 In a study of Lycopene and 1,25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells, researchers found that The combination of low concentrations of lycopene with 1,25-dihydroxyvitamin D3 exhibited a synergistic effect on cell proliferation and differentiation and an additive effect on cell cycle progression. Such synergistic antiproliferative and differentiating effects of lycopene and other compounds found in the diet and in plasma may suggest the inclusion of the carotenoid in the diet as a cancer-preventive measure. e. Selenium In a study of Selenium-induced Cytotoxicity of Human Leukemia Cells Interaction with Reduced Glutathione, researchers suggested that Only selenocystine and sodium selenite showed anti-tumor activity, and these were also the only compounds which demonstrated significant redox chemistry, including depletion of cellular glutathione, stimulation of glutathione reductase, and stimulation of oxygen consumption. The interaction of these two compounds with glutathione suggests an intriguing potential role for them in cancer therapy. g. Etc. A.5. Treatments 1. In conventional medicine The objective of the treatment of AML is to cure the a patient a. Induction therapy The purpose of induction therapy is to used certain chemotherapy drugs, such as daunorubicin, adriamycin, etc. to reduce the number of cancer cells to see if the disease is responded and goes into remission. If it does, the next step of bone marrow transplant enhances the curative chance to over 50%. b. Bone marrow transplant Bone marrow transplant with bone marrow taken from a closed relative with the same tissue type. After surgery, medicine is taken for a long time to prevent the rejection of the patient body. patient with bone marrow transplant are required to be in intensive care and isolation to avoid infection for the new bone marrow to grow. c. Etc. 2. Herbal medicine a. Nettle Nettle or stinging nettle, is a perennial plant growing in temperate and tropical wasteland areas around the world, genus Urtica, belonging to the family Urticaceae. In some studies, research found that nettle's anti-inflammatory actions are attributed to its ability to interrupt the production and actions of inflammation-producing immune cells in the body (cytokines, prostaglandins and leukotreines). b. St. John's wort St John's wort is also known as Tipton's Weed, genus Hypericum, belonging to the family Hypericaceae, native to North America, Europe, Turkey, Russia, India, and China. A study published in the journal Cancer stated that an man-made version of hypericin, which naturally occurs in St. John's wort, appears to inhibit the growth of some malignant brain tumors. c. Absinthe Absinthe is also known as Wormwood, a distilled, highly alcoholic beverage flowers extracted from leaves of the herb Artemisia absinthium. In a study, researcher at the University of Washington found that wormwood can be used as a promising potential treatment for cancer among the ancient arts of Chinese folk medicine. d. Celandine Celandine is a herbaceous perennial plant, genus Chelidonium, belonging to the family Papaveraceae, native to Europe and western Asia and introduced widely in North America. In a study of Ukrain (Ukrain is an anticancer drug based on the extract of the plant)&ndash; a new cancer cure? A systematic review of randomised clinical trials, researcher suggested, according to the data from randomised clinical trials that Ukrain to have potential as an anticancer drug. However, numerous caveats prevent a positive conclusion, and independent rigorous studies are urgently needed. e. Myrrh Myrrh is the dried oleo gum resin of a number of Commiphora or dhidin species of trees containing high amount of Boswellic acids. in a study, reported in In Vitro Screening for the Tumoricidal Properties of International Medicinal Herbs showed that Boswellic acids exert direct antiproliferative/pro-apoptotic effects through activation of caspase-3/8/9 and PARP cleavage in HT-29 cells (Liu et al., 2002), human leukemia cells HL-60, K 562, U937, MOLT-4, THP-1 and brain tumor cells LN-18, LN-229 (Hostanska et al., 2002). f. Etc. 3. Traditional Chinese medicine a. Shan Dou Gen Shan Dou Gen is also known as sophora root. The bitter, cold and toxic herb has been used in TCM to hemorrhoids, cancer of the bladder, acute tonsillitis, psoriasis, hepatitis due to viral infection, etc. In a study, researcher found that purified compound Shan Dou Gen induced apoptosis in human leukemia cells and identified it as sophoranone... Our results indicate that sophoranone might be a unique apoptosis-inducing anticancer agent that targets mitochondria." Int J Cancer 2002 Jun 20;99(6):879-90 b. Ling Zhi Ling Zhi is also known as Reishi mushroom. The sweet and neutral herb has been used in TCM as anti-inflammatory and antioxidation agent and to promote immunomodulary activityand mitochondrial energy production and prevent neuronal loss following cerebral ischemia, etc. In Aaseries of experiments including cell culture and benzidine staining test were undertaken to investigate the effects of Ganoderma lucidum(Leyss ex Fr) Karst Compound(GLC) on the proliferation and differentiation of K562 leukemic cells... It is concluded that GLC may be a good medicine for leukemia therapy." Hunan Yi Ke Da Xue Xue Bao. 1999;24(6):521-4. Chinese. c. Jie Geng Jie geng is also known as Platycodon Root. The acrid, bitter and neutral herb has been use in TCM as anti-inflammatory, anti ulcers agent and to inhibit cough, treat bronchitis, sore throat etc., as it stimulates the lung in dispersing and descending functions, transforms phlegm, etc., by enhancing the functions of the lung channels.The Researchers found that Saponins in Jie Geng have been shown to very significantly augment the cytotoxicity of immunotoxins and other targeted toxins directed against human cancer cells. d. Xia Ku Cao Xia Ku Cao is also known as Common Selfheal Fruit-Spike. The acrid, bitter and cold herb has ben used in TCM as diuretic, antibiotic agent and to treat hypertension and arteriosclerosis, acute tonsillitis, amnesia, whooping cough etc., as it disperses Liver-Fire and nodules, treat hypotension, etc. by enhancing the functions of liver and gallbladder channels. Researchers found that cyasterone in Xia Ku Cao showed anti tumor activity. 5. Qing hao Qing hao is also known as wormwood. The bitter and cold herb has been used in TCM to trea lupus, schistosomiasis, chronic bronchitis (essential oil) to elevate the calcium ions of leukemia white cells, etc. In a study, researcher at the University of Washington researcher found that wormwood can be used as a promising potential treatment for cancer among the ancient arts of Chinese folk medicine. 6. Etc. For other health articles, please visit If you like what you read, please follow me at Visit site: http://gameone.club/ get off my internets blogging away debt jim nabors
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